CAT 2025 Slot 3 VARC Q13 Sentence Placement

Question 13 of the Verbal Ability & Reading Comprehension (VARC) section, CAT 2025 Slot 3, with CAT's official answer and a worked solution.

The given sentence is missing in the paragraph below. Decide where it best fits among the options 1, 2, 3, or 4 indicated in the paragraph.

Sentence: In each of the affected males, the genetic defect was located to the X chromosome in the region of p11-12.

Paragraph: The first suggested evidence of a human genetic mutation associated with aggressive behaviour came from a study in 1993. _____(1)____. Genetic and metabolic studies were conducted on a large Dutch family in which several of the males has a syndrome of borderline mental retardation and abnormal behaviour. _____(2)____. The undesirable behaviour included impulsive aggression, arson and exhibitionism. _____(3)____. A point mutation was identified in the eighth exon of the monoamine oxidase A (MAOA) structural gene which changes glutamine to a termination codon. _____(4)____.
  1. A
    Option 2
  2. B
    Option 1
  3. C
    Option 3
  4. D
    Option 4

Answer: (C) Option 3 Sentence Placement MCQ

Solution

  1. The paragraph moves from the study, to the Dutch family, to their behaviour, then to the precise mutation in the MAOA gene.
  2. Locating the defect on the X chromosome (p11-12) narrows the search before 'A point mutation was identified in the eighth exon' gives the exact site.
  3. So it fits at blank 3, after the behaviour description and before the point mutation: Option 3.